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Estrogen dominance contributes to a number of adverse health conditions including weight gain, PMS, Uterine fibroids and cancer of the breast, ovaries, uterus and prostate. If you are estrogen dominant it is almost impossible to lose weight. E-Dominance detoxes and eliminates bad estrogen metabolites (04 & 16) while enhancing favorable protective 02 metabolite. When men reach 30 years of age their testosterone decreases and estrogen increases which may result in man boobs and prostrate problems. E-Dominance reduces the estrogen and increases free testosterone. It is also effective in detoxing micotoxins derived from mold from the body.